The Wallabies will be desperate to bounce back as they travel to Dublin to face Ireland.
Dave Rennie's men were shocked by Italy, suffering their second-straight one point defeat after going down in Florence.
They face an Irish side brimming with confidence, eager to cement their status as the number-one team in the world.
The hosts are coming off a comfortable 35-17 win over Fiji, set to welcome back a host of stars, including Johnny Sexton.
Here is everything you need to know about Ireland v Wallabies
WHEN DO THE WALLABIES PLAY NEXT?
The Wallabies will next play Ireland on November 20 (AEDT) in Florence
It will be the fourth match in a gruelling five-Test Spring Tour, followed by a trip to Cardiff to take on Wales
Dave Rennie's men started the tour with a win over Scotland before narrow defeats to France and Italy.
HOW TO WATCH WALLABIES v IRELAND IN AUSTRALIA?
The Wallabies' clash with Ireland will be shown LIVE on Stan Sport.
Coverage will be live and ad-free on Stan Sport, slated to start at 6:40 am AEDT with kickoff expected at 7:00 am AEDT.
The game will not be shown on free-to-air like in previous years, with anti-siphoning laws only covering home and All Blacks Tests.
HOW TO WATCH WALLABIES V IRELAND OVERSEAS
New Zealand: Sky Sports
South Africa/Africa and adjacent islands: SuperSport
Argentina/South America/North America: ESPN
Ireland and UK (England, Scotland, Wales, Northern Ireland, Channel Islands, Isle of Man): Sky UK
Italy, Vatican City, San Marino and Canton Ticino, Switzerland: Sky Italia
Asia-Pacific, Bangladesh, Bhutan, Brunei, Burma (Myanmar), Cambodia, Federated States of Micronesia, Hong Kong, Indonesia, Kiribati, Kyrgyzstan, Laos, Macau, Malaysia, Maldives, Marianas, Marshall Islands, Mongolia, Nepal,Northern Marianas, North Korea, Pakistan, Palau, Philippines, Singapore,South Korea, Tajikistan, Taiwan (Republic of China), Thailand, Timor-Leste,Vietnam: Premier Sports
Africa and adjacent islands:SuperSport
SPRING TOUR FIXTURES
Wallabies 16 def Scotland 15, Sunday 30 October, 3:30am AEDT at BT Murrayfield, Edinburgh
Wallabies 29 def by France 30, Sunday 6 November, 7:00am AEDT at Stade de France, Paris
Wallabies 27 def by Italy 28, Sunday 13 November, 12:00am AEDT at Stadio Artemio Franchi, Florence
Wallabies v Ireland, Sunday 20 November, 7:00am AEDT at Aviva Stadium, Dublin
Wallabies v Wales, Sunday 27 November, 2:15am AEDT at Principality Stadium, Cardiff
WHEN IS THE WALLABIES v IRELAND KICK OFF?
The Test between the Wallabies and Ireland will kick off at 7:00 am AEDT at Aviva Stadium on Sunday November 20 (AEDT)
Coverage will be ad-free from 6:40 am AEDT and continue throughout the game on Stan Sport.
IRELAND v WALLABIES TEAMS
WALLABIES (15-1): Andrew Kellaway; Mark Nawaqanitawase, Len Ikitau, Hunter Paisami, Tom Wright; Bernard Foley, Nic White; Rob Valetini, Michael Hooper, Jed Holloway; Cadeyrn Neville, Nick Frost; Allan Alaalatoa, David Porecki, James Slipper (capt)
Replacements: Folau Fainga'a, Tom Robertson, Taniela Tupou, Will Skelton, Pete Samu, Jake Gordon, Noah Lolesio, Jordan Petaia
IRELAND (15-1): Hugo Keenan; Mack Hansen, Garry Ringrose, Stuart McCloskey, Jimmy O'Brien; Johnny Sexton (capt), Jamison Gibson-Park; Caelan Doris, Josh van der Flier, Peter O'Mahony; James Ryan, Tadhg Beirne; Tadhg Furlong, Dan Sheehan, Andrew Porter
Replacements: Rob Herring, Cian Healy, Finlay Bealham, Joe McCarthy, Jack Conan, Craig Casey, Jack Crowley, Bundee Aki